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Sr Director, Specialty Portfolio (Generics)

MCKESSON

Irving, Texas, U.S.
Full-time, Regular
Posted Nov 10, 2025
Onsite

Compensation

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About the role

The Sr. Director, Specialty Portfolio provides strategic leadership and operational oversight for McKesson’s generics portfolio, supporting the Specialty Provider (clinic) channel and generic injectables across all other channels via the Passport program.

Responsibilities

  • Develop molecule-level strategies to ensure supply redundancy and competitive sourcing across channels.
  • Manage vendor share expectations and coordinate execution across internal teams.
  • Evaluate private label pipeline targets and collaborate on share allocations, pricing, and launch timing.
  • Guide commercialization efforts for new products and market entrants.
  • Incorporate clinical and customer feedback into portfolio strategy.
  • Make strategic decisions balancing competing priorities and driving enterprise value.
  • Establish and evolve business processes to monitor portfolio health and mitigate risk.
  • Implement operational policies and models, including ClarusONE-driven activities.
  • Lead cross-functional collaboration to support accurate forecasting, inventory management, and buyside operations.
  • Analyze cost structures of key generic drugs and lead quarterly market reviews.
  • Drive business development efforts with manufacturers to optimize cost and maximize gross profit.
  • Execute strategic buys and inventory decisions aligned with customer needs.

Requirements

  • Extensive experience in portfolio management, supply chain, operations, or business development.
  • Strong background in pharmaceutical purchasing, distribution, and generic market dynamics.
  • B2B experience with pharmaceutical, biotech, or healthcare organizations.
  • Familiarity with specialty clinic operations and generic pharmaceuticals.
  • Proficiency in Power BI and Smartsheet.

Benefits

  • 401k matching
  • Health insurance
  • Flight privileges
  • ProfitSharing contribution
  • Competitive health insurance

About the Company

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare.

Job Details

Salary Range

Salary not disclosed

Location

Irving, Texas, U.S.

Employment Type

Full-time, Regular

Original Posting

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